Injectable Polynucleotides

Plinest

At bare. BEAUTY, I use Plinest, an Italian polynucleotide treatment designed to support natural skin regeneration and improve overall skin quality.

What are Polynucleotides and how do they support skin regeneration? ?

Polynucleotides are purified DNA-derived molecules, traditionally sourced from salmon or trout, used in aesthetic medicine to support skin rejuvenation.

Unlike traditional dermal fillers, which primarily restore volume, polynucleotides work with your skin’s natural renewal processes to support hydration, elasticity and collagen production.

This makes them particularly suited to delicate areas showing early signs of ageing, fine lines, crepey texture or a loss of firmness.

Treatments can be tailored to areas including the eyes, face, neck, hands and décolletage, depending on the individual product and your skin’s needs.

What should I expect at my appointment?

A series of small, carefully placed injections will deliver the product directly into your skin, focusing on areas such as delicate eye contour, face or neck. You may feel a slight pinching sensation during the injections, but the treatments is generally well tolerated. Small, raised bumps may be visible at the injection sites immediately afterwards, alongside some redness or swelling. These usually settle naturally over the following days.

Downtime:

• Mild redness or swelling for 24–48 hours

• Possible minor bruising

• Most clients return to normal activities immediately

How many sessions will I need?

For optimal results, I recommend an initial course of 3 polynucleotide treatments, typically spaced 4 weeks apart. Following your initial course, maintenance treatments can be considered approximately every 9–12 months, depending on your skin’s response and individual needs.

During your consultation, we’ll discuss your concerns, the most suitable treatment area and a personalised plan for your skin.

When will I see results?

Unlike treatments designed to create an immediate change in volume, polynucleotides work progressively, supporting improvements in hydration, texture, elasticity and overall skin quality over time.

How should I prepare for my treatment?

Avoid alcohol for 24 hours before treatment and ensure your skin is free from active infections or irritation. Please inform me of any allergies, particularly fish allergies, medication or recent aesthetic treatments, allowing us to plan your treatment safely and comfortably.

What aftercare should I follow?

Following your polynucleotide treatment, you may experience small raised bumps, mild swelling, redness or bruising around the injection sites. These are normal temporary reactions and usually settle over the following few days.

Avoid touching or massaging the treated area, applying makeup for 24 hours, and strenuous exercise, alcohol, saunas and excessive heat for 24–48 hours. Keep your skincare gentle and apply SPF 50+ daily.

Full personalised aftercare guidance will be provided at your appointment.

PRE & AFTER CARE ADVICE